Methylsulfonylmethane, often abbreviated to MSMS, is not only a mouthful, but offers a truly impressive wealth of health benefits for a range of issues. Popularized many years ago as an anti-inflammatory supplement for osteoarthritis pain, its benefits have been proven in animal and human studies to reach far beyond joint pain.
What Is MSM (Methylsulfonylmethane)?
Methylsulfonylmethane (which can also go by dimethyl sulfone, methyl sulfone, sulfonylbismethane, organic sulfur, or crystalline dimethyl sulfoxide) was actually used first in the 50s as a commercial solvent. (1) It wasn’t until the 70s that the medical community began recognizing its unique and far reaching anti-inflammatory and antioxidative properties.
5 Evidence-Based Benefits of MSM Supplements
One could argue that a supplement that is anti-inflammatory and anti-oxidative has nearly endless potential benefits, the following are five areas with a lot of scientific evidence to back up its efficacy.
1. Treating joint pain and soreness
Studies have repeatedly shown MSM’s efficacy in reducing joint pain, especially pain associated with osteoarthritis. (2) It has also been shown to help reduce acute soreness associated with heavy exertion and exercise. (3)
2. Promoting joint mobility
Studies have also shown that in addition to reducing/preventing pain, MSM supplementation can actually help people improve their range of motion. As a combined effect, this with pain reduction can have life-changing effects on anyone struggling with disease or injury that affect mobility. And with daily movement being a key tenet of health, these combined outcomes can dramatically improve someone’s overall well-being and recovery outcomes.
3. Skin benefits
Pain-free and beautiful too? While less imperative to health than joint mobility and pain prevention, glowing, youthful skin is no small thing to many people. MSM has been shown in clinical studies to help improve pigmentation, skin elasticity, and reduce wrinkling. (3) This is not surprising given the impact we know antioxidants support skin health. MSM can be a great tool in your functional medicine beauty toolkit.
4. Allergies
Whether you’re in the thick of hay fever or cursing the dust in your own home, battling allergies can be incredibly frustrating. One study found MSM to be supportive in individual managing their allergy symptoms, though it’s important to note the study did find that MSM had an effect on histamine levels. (4)
5. Possible cancer prevention
Emerging science suggests that MSM may be a promising supplement in cancer prevention. Several in vitro studies have seen the compound’s ability to kill or prevent cancer cells. Though additional research is required to confirm this in real human subjects, it’s exciting to see new ways functional health staples applied in cancer prevention.(4)
Is MSM Found Naturally in Foods?
MSM is found naturally in many foods (even that thing you probably start your day with and drink too much of), although its dietary levels tend to be much smaller than what would be used in supplements for a therapeutic effect.MSM can be found in:
- Your morning cup of coffee
- Protein-rich foods like eggs, fish, poultry, and red meat
- Cooking staples like onions and garlic
- Plant food powerhouses like raspberries, leafy greens, and alfalfa sprouts
It’s important to note that MSM can be easily destroyed in foods with any processing so be sure to prioritize real foods with the least amount of processing possible.
What Is the Recommended Dosage for MSM Supplements?
MSM commonly is given as 2 to 6 grams per day, usually divided in doses. But as with most supplements, it’s best to consult an expert and use a dose that targets your specific concerns.
Risks and Side Effects of MSM Supplements
While there are very few observed risks of MSM, you should consult an expert on how this medication might interact with your other supplements and medications. It may cause mild stomach upset in the form of nausea, constipation, or diarrhea.
Potential interactions include:
- blood clot prevention medications
- NSAID (non-steroidal anti-inflammatory drugs) like ibuprofen
- Various herbal supplements
How to Choose an MSM Supplement
MSM is often combined with other compounds to target specific concerns, so taking it in isolation may not be the most effective option. A couple options we can personally vouch for:
- h o l i ( r a d i a n c e ) (supports: immunity, mobility, and an overall glow)
- Protect (supports: detoxification)
Schedule a consultation today to learn about the best combination for you.
The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.
Our content may include products that have been independently chosen and recommended by Dr. Will Cole and our editors. If you purchase something mentioned in this article, we may earn a small commission.
